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Use only on cats and kittens 12 weeks of age and older. For fleas: This collar is designed to kill adult fleas and flea eggs. It begins working to kill fleas and flea eggs as soon as it is placed around eh cat's neck. Protection against fleas and flea eggs will be achieved within 48 hours, providing continuous protection for 8 months. Replace collar every 8 months. For ticks: Full protection against adult and immature ticks will be achieved within a few days, providing continuous protection for up to 6 months. Adult ticks will be killed over the entire pet. Dead ticks will fall off or may be easily removed. Active Ingredients: Propoxur (10%), S-Methoprene (2.1%).